Nature's chemicals and synthetic chemicals: comparative toxicology.

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Nature's chemicals and synthetic chemicals: comparative toxicology.

The toxicology of synthetic chemicals is compared to that of natural chemicals, which represent the vast bulk of the chemicals to which humans are exposed. It is argued that animals have a broad array of inducible general defenses to combat the changing array of toxic chemicals in plant food (nature's pesticides) and that these defenses are effective against both natural and synthetic toxins. S...

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Predictive Toxicology and Mixtures of Chemicals

All predictive toxicological models concern individual chemicals. An exposure to a mixture of chemicals is the reality, however. Toxicity of an individual chemical itself or in a mixture with other chemicals may significantly differ. The presentation shows our attempt to find a suitable model for a prediction of acute toxicity of binary mixtures of organic chemicals. We have suggested a molar r...

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ژورنال

عنوان ژورنال: Proceedings of the National Academy of Sciences

سال: 1990

ISSN: 0027-8424,1091-6490

DOI: 10.1073/pnas.87.19.7782